NRIP1

Across TCGA patient cohorts, NRIP1 mutation is significantly associated with the RNA expression of many other genes, with 6,638 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NRIP1-associated genes across cancer lineages are FAXDC2, MYL12BP1, and PRF1. Each is linked with NRIP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both NRIP1-to-partner and partner-to-NRIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAXDC2 grouped by NRIP1-low versus NRIP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NRIP1→partner) and Y-score (partner→NRIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FAXDC2 →	-0.631	-1.584	<.001	<.001	3	4
UCEC	MYL12BP1 →	+0.378	+1.803	<.001	<.001	3	4
UCEC	PRF1 →	+1.092	+2.571	<.001	<.001	3	3
UCEC	GLRX5 →	+0.360	+1.782	<.001	<.001	3	3
UCEC	UBE2L3 →	+0.345	+1.771	<.001	<.001	3	3
UCEC	ZNF511 →	+0.303	+1.828	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,638 associations by consensus.

FAXDC2 by NRIP1 expression — UCEC

Explore this box plot interactively →