NRIP1

Across TCGA cell cohorts, NRIP1 mutation is significantly associated with the RNA expression of many other genes, with 661 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NRIP1-associated genes across cancer lineages are AVP, ZAN, and FTMT. Each is linked with NRIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NRIP1-to-partner and partner-to-NRIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by NRIP1-low versus NRIP1-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NRIP1→partner) and Y-score (partner→NRIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	AVP →	+0.097	+4.977	<.001	.002	3	1
SOFT_TISSUE	ZAN →	+0.004	+4.369	<.001	.008	3	1
SOFT_TISSUE	FTMT →	+0.065	+4.977	<.001	.002	3	1
SOFT_TISSUE	PRAMEF17 →	+0.014	+4.369	<.001	.008	3	1
SOFT_TISSUE	PRAMEF18 →	+0.022	+5.515	<.001	<.001	3	1
OESOPHAGUS	SCN2B →	+0.030	+3.584	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 661 associations by consensus.

AVP by NRIP1 expression — SOFT_TISSUE

Explore this box plot interactively →