Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts
Across TCGA cell cohorts, NRG3 mutation is significantly associated with the RNA expression of many other genes, with 535 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.
The most reproducible NRG3-associated genes across cancer lineages are GSG1L2, PPP1R8, and DHX30. Each is linked with NRG3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NRG3-to-partner and partner-to-NRG3 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (NRG3→partner) and Y-score (partner→NRG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.