NREP

Across TCGA patient cohorts, NREP RNA expression is significantly associated with the protein abundance of many other proteins, with 16,679 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NREP-associated proteins across cancer lineages are MMP2, DBN1, and DPYSL3. Each is linked with NREP in more than 7 cancer types. Because this analysis shows association rather than direction, both NREP-to-partner and partner-to-NREP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NREP versus MMP2 in BRCA, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NREP→partner) and Y-score (partner→NREP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MMP2 →	+0.779	+0.559	<.001	<.001	3	8
OV	DBN1 →	+0.624	+0.561	.004	.003	3	8
BRCA	DPYSL3 →	+0.669	+0.531	<.001	<.001	3	8
COAD	ANTXR1 →	+0.617	+0.393	<.001	<.001	3	7
LSCC	PCOLCE →	+0.775	+0.647	<.001	<.001	3	7
BRCA	PTK7 →	+0.529	+0.429	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,679 associations by consensus.

NREP vs MMP2 — BRCA

Explore this scatter interactively →