NREP-AS1

Across TCGA patient cohorts, NREP-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 6,509 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible NREP-AS1-associated proteins across cancer lineages are SHARPIN_S165, EPB41L4A_S543, and OBI1_S553. Each is linked with NREP-AS1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NREP-AS1-to-partner and partner-to-NREP-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NREP-AS1 versus SHARPIN_S165 in PDAC, with a Pearson correlation of -0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NREP-AS1→partner) and Y-score (partner→NREP-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	SHARPIN_S165 →	-0.471	-0.405	<.001	<.001	3	3
LUAD	EPB41L4A_S543 →	+0.711	+0.743	<.001	.001	3	3
LUAD	OBI1_S553 →	-0.401	-0.733	.007	.007	3	3
LUAD	PLEKHA7_S117 →	+0.933	+0.571	.001	.002	3	2
LUAD	C5orf24_S121 →	+0.641	+0.933	.002	.007	3	2
LUAD	CRYM →	+0.980	+0.607	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,509 associations by consensus.

NREP-AS1 vs SHARPIN_S165 — PDAC

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