NRDC

Across TCGA cell cohorts, NRDC RNA expression is significantly associated with the go_rna of many other GO terms, with 4,053 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NRDC-associated GO terms across cancer lineages are Regulation of centrosome cycle, Microtubule organizing center organization, and Microtubule polymerization. Each is linked with NRDC in more than 14 cancer types. Because this analysis shows association rather than direction, both NRDC-to-partner and partner-to-NRDC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of centrosome cycle grouped by NRDC-low versus NRDC-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NRDC→partner) and Y-score (partner→NRDC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of centrosome cycle →	+0.111	+0.557	.006	.004	3	15
LUNG_NSCLC_LUSC	Microtubule organizing center organization →	+0.084	+1.007	.001	.002	3	14
LARGE_INTESTINE	Microtubule polymerization →	+0.111	+0.603	.001	.003	3	14
LUNG_NSCLC_LUSC	Centrosome cycle →	+0.094	+0.948	.001	.005	3	14
LARGE_INTESTINE	Nuclear transport →	+0.073	+0.740	<.001	<.001	3	14
LARGE_INTESTINE	Nucleocytoplasmic transport →	+0.073	+0.771	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,053 associations by consensus.

Regulation of centrosome cycle by NRDC expression — OESOPHAGUS

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