Across TCGA cell cohorts, NRBP2 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NRBP2-associated genes across cancer lineages are DRD3, PTH, and PRG3. Each is linked with NRBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NRBP2-to-partner and partner-to-NRBP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NRBP2→partner) and Y-score (partner→NRBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	DRD3 →	+0.017	+5.562	<.001	<.001	3	1
LARGE_INTESTINE	PTH →	+0.063	+4.684	<.001	.002	3	1
LARGE_INTESTINE	PRG3 →	+0.021	+4.415	<.001	.007	3	1
LARGE_INTESTINE	P2RY12 →	+0.135	+4.273	.001	.006	3	1
LARGE_INTESTINE	ZNF804B →	+0.011	+4.415	.009	.007	3	1
LARGE_INTESTINE	OR4F5 →	+0.028	+4.930	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

NRBP2 survival (RNA) · tumor vs normal (RNA) · all NRBP2 data types