NRBF2P4

Across TCGA pan-cancer cohorts, NRBF2P4 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated NRBF2P4 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher NRBF2P4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NRBF2P4 expression acts as an unfavorable survival marker, although some lineages such as SKCM and KIRC show a favorable association.

BRCA, SKCM, and DLBC are the cancer types where NRBF2P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Tertile	All	0.917	0.959	<.001	105	view →
SKCM	OS	Tertile	II,III,IV	0.843	0.692	.002	42	view →
DLBC	OS	Tertile	II,III,IV	0.172	0.949	<.001	36	view →
THYM	OS	Tertile	III,IV	0.229	1.000	<.001	27	view →
THCA	OS	Tertile	IV	0.512	0.924	.003	24	view →
SARC	OS	Tertile	All	0.762	0.858	.005	18	view →
BLCA	OS	Tertile	III,IV	0.202	0.429	.032	9	view →
KIRC	DFS	Tertile	IV	0.912	0.519	.041	6	view →
ESCA	DFS	Tertile	All	0.269	0.793	.011	6	view →
GBM	OS	Quartile	All	0.344	0.476	.024	6	view →
COAD	DFS	Tertile	III,IV	0.512	0.728	.044	3	view →
CESC	OS	Quartile	All	0.722	0.519	.044	2	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

NRBF2P4–BRCA (DFS)

Open the BRCA breakdown →