NRBF2P4

Across TCGA pan-cancer cohorts, NRBF2P4 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of NRBF2P4’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where NRBF2P4 RNA is repressed in tumor relative to normal tissue. In most cancer types NRBF2P4 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.

LUSC and KICH are the cancer types where NRBF2P4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NRBF2P4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	II,III,IV	−0.044	.002	2	view →
KICH	Female	All	+0.022	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

NRBF2P4–LUSC

Open the LUSC breakdown →