Across TCGA patient cohorts, NRAS protein abundance is significantly associated with the RNA expression of many other genes, with 7,074 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NRAS-associated genes across cancer lineages are CANT1, VANGL1, and STRIP1. Each is linked with NRAS in more than 2 cancer types. Because this analysis shows association rather than direction, both NRAS-to-partner and partner-to-NRAS results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NRAS→partner) and Y-score (partner→NRAS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CANT1 →	-0.575	-0.484	.001	.003	3	3
LSCC	VANGL1 →	+0.550	+0.250	<.001	<.001	3	3
GBM	STRIP1 →	+0.351	+0.224	.003	.008	3	3
GBM	MYL12A →	-0.775	-0.303	<.001	<.001	3	2
COAD	TRADD →	-0.408	-0.500	.001	.001	3	2
GBM	ARRDC2 →	-0.447	-0.228	.009	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,074 associations by consensus.

Exploration

NRAS survival (RNA) · tumor vs normal (RNA) · all NRAS data types