Across TCGA cell cohorts, NRAP mutation is significantly associated with the RNA expression of many other genes, with 530 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NRAP-associated genes across cancer lineages are CFAP97, C4orf46, and GCM2. Each is linked with NRAP in more than 2 cancer types. Because this analysis shows association rather than direction, both NRAP-to-partner and partner-to-NRAP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NRAP→partner) and Y-score (partner→NRAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CFAP97 →	+0.661	+1.949	<.001	.002	3	3
LARGE_INTESTINE	C4orf46 →	+0.596	+2.036	<.001	.002	3	3
OESOPHAGUS	GCM2 →	+0.017	+3.584	<.001	.008	3	2
OESOPHAGUS	CDCP2 →	+0.019	+3.652	.001	.006	3	2
BLOOD_Myeloma	OR1B1 →	+0.087	+3.736	<.001	.004	3	2
LARGE_INTESTINE	HMGXB4 →	+0.520	+3.339	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 530 associations by consensus.

Exploration

NRAP survival (RNA) · tumor vs normal (RNA) · all NRAP data types