NR6A1

Across TCGA patient cohorts, NR6A1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,781 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NR6A1-associated proteins across cancer lineages are SMC1A, SMC3, and STAG2. Each is linked with NR6A1 in more than 7 cancer types. Because this analysis shows association rather than direction, both NR6A1-to-partner and partner-to-NR6A1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NR6A1 versus SMC1A in LSCC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NR6A1→partner) and Y-score (partner→NR6A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SMC1A →	+0.334	+0.781	<.001	<.001	3	8
LSCC	SMC3 →	+0.350	+0.707	<.001	<.001	3	7
GBM	STAG2 →	+0.303	+0.571	<.001	<.001	3	7
GBM	HCFC1 →	+0.213	+0.564	.002	<.001	3	7
LSCC	STRBP →	+0.448	+0.490	<.001	<.001	3	6
GBM	WDR5 →	+0.274	+0.638	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,781 associations by consensus.

NR6A1 vs SMC1A — LSCC

Explore this scatter interactively →