NR6A1

Across TCGA patient cohorts, NR6A1 mutation is significantly associated with the RNA expression of many other genes, with 3,841 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NR6A1-associated genes across cancer lineages are RNA5SP413, RN7SL478P, and RN7SKP245. Each is linked with NR6A1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NR6A1-to-partner and partner-to-NR6A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP413 grouped by NR6A1-low versus NR6A1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NR6A1→partner) and Y-score (partner→NR6A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP413 →	+1.382	+2.429	<.001	<.001	3	3
READ	RN7SL478P →	+0.216	+5.219	<.001	.006	3	2
READ	RN7SKP245 →	+0.216	+7.276	<.001	<.001	3	2
BLCA	PPIAL4F →	+0.073	+4.299	.007	.007	3	2
UCEC	MCM5 →	+0.623	+3.480	.002	.002	3	2
UCEC	ACTR1A →	+0.411	+3.584	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,841 associations by consensus.

RNA5SP413 by NR6A1 expression — UCEC

Explore this box plot interactively →