NR4A3

Across TCGA cell cohorts, NR4A3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,192 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible NR4A3-associated GO terms across cancer lineages are Response to corticotropin-releasing hormone, Cellular response to corticotropin-releasing hormone stimulus, and Plasma lipoprotein particle organization. Each is linked with NR4A3 in more than 9 cancer types. Because this analysis shows association rather than direction, both NR4A3-to-partner and partner-to-NR4A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to corticotropin-releasing hormone grouped by NR4A3-low versus NR4A3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NR4A3→partner) and Y-score (partner→NR4A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Response to corticotropin-releasing hormone →	+0.946	+0.909	<.001	.007	3	10
BONE	Cellular response to corticotropin-releasing hormone stimulus →	+0.902	+0.909	<.001	.007	3	9
SOFT_TISSUE	Plasma lipoprotein particle organization →	+0.095	+0.432	<.001	.006	3	6
OVARY	Establishment of vesicle localization →	+0.033	+0.637	<.001	.009	2	7
SKIN	Pigmentation →	+0.132	+2.483	<.001	<.001	3	6
BLOOD_Leukemia	Positive regulation of mast cell activation →	-0.495	-0.264	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,192 associations by consensus.

Response to corticotropin-releasing hormone by NR4A3 expression — BONE

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