NR2F2-AS1

Across TCGA pan-cancer cohorts, NR2F2-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated NR2F2-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher NR2F2-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NR2F2-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and KIRP show a favorable association.

ACC, LGG, and UVM are the cancer types where NR2F2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.284	0.604	<.001	90	view →
LGG	DFS	Median	All	0.663	0.812	<.001	49	view →
UVM	DFS	Quartile	II,III,IV	0.616	0.958	.004	48	view →
UCS	DFS	Median	II,III,IV	0.596	0.281	.010	26	view →
LUAD	DFS	Quartile	III,IV	0.488	0.731	.015	18	view →
KIRP	DFS	Tertile	All	0.967	0.855	.003	14	view →
KIRC	OS	Median	All	0.903	0.842	.003	13	view →
SKCM	OS	Quartile	IV	0.845	0.306	.016	13	view →
BLCA	OS	Tertile	All	0.421	0.642	.023	12	view →
GBM	DFS	Median	All	0.203	0.307	.007	12	view →
LIHC	DFS	Tertile	III,IV	0.496	0.149	.003	12	view →
THCA	DFS	Tertile	IV	0.910	0.573	.012	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

NR2F2-AS1–ACC (DFS)

Open the ACC breakdown →