NR2F2-AS1

Across TCGA pan-cancer cohorts, NR2F2-AS1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of NR2F2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where NR2F2-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types NR2F2-AS1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, THCA, and LUSC are the cancer types where NR2F2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NR2F2-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	−2.038	<.001	11	view →
THCA	Female	II,III,IV	−0.351	<.001	11	view →
LUSC	All	III,IV	−1.006	<.001	9	view →
LUAD	Female	III,IV	−0.760	<.001	8	view →
COAD	All	II,III,IV	−0.193	<.001	8	view →
UCEC	All	All	−1.318	<.001	6	view →
BRCA	All	II,III,IV	−0.444	<.001	6	view →
CHOL	All	All	+0.753	.002	2	view →
READ	All	All	−0.378	.009	2	view →
KIRP	All	All	−0.345	.020	2	view →
PRAD	All	All	−0.231	.002	2	view →
LIHC	All	All	+0.123	.035	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

NR2F2-AS1–KICH

Open the KICH breakdown →