NR2F1

Across TCGA patient cohorts, NR2F1 mutation is significantly associated with the RNA expression of many other genes, with 1,845 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NR2F1-associated genes across cancer lineages are RNU6-1316P, OR11H6, and BSPH1. Each is linked with NR2F1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NR2F1-to-partner and partner-to-NR2F1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1316P grouped by NR2F1-low versus NR2F1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NR2F1→partner) and Y-score (partner→NR2F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-1316P →	+0.248	+2.843	<.001	.002	3	3
ACC	OR11H6 →	+0.060	+5.228	<.001	.005	3	2
ACC	BSPH1 →	+0.057	+5.228	<.001	.005	3	2
ACC	IFNWP9 →	+0.061	+5.228	.004	.005	3	2
ACC	HEBP2P1 →	+0.059	+4.887	<.001	.009	3	2
ACC	LINC00391 →	+0.026	+5.662	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,845 associations by consensus.

RNU6-1316P by NR2F1 expression — SKCM

Explore this box plot interactively →