NR2F1-AS1

Across TCGA pan-cancer cohorts, NR2F1-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated NR2F1-AS1 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher NR2F1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NR2F1-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and SKCM show a favorable association.

BLCA, KIRP, and UVM are the cancer types where NR2F1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	All	0.327	0.576	<.001	142	view →
KIRP	OS	Median	II,III,IV	0.360	0.712	<.001	141	view →
UVM	OS	Median	All	0.439	0.889	<.001	116	view →
KIRC	OS	Tertile	All	0.865	0.750	<.001	57	view →
SKCM	OS	Tertile	All	0.823	0.706	.003	36	view →
LGG	DFS	Tertile	All	0.426	0.288	.003	28	view →
STAD	OS	Median	All	0.512	0.643	.012	19	view →
COAD	DFS	Tertile	All	0.600	0.768	.007	16	view →
MESO	OS	Tertile	IV	0.818	0.318	.013	12	view →
GBM	OS	Median	All	0.344	0.472	.005	12	view →
OV	OS	Tertile	III,IV	0.257	0.365	.014	12	view →
THCA	DFS	Quartile	II,III,IV	0.584	0.873	.011	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

NR2F1-AS1–BLCA (OS)

Open the BLCA breakdown →