Across TCGA pan-cancer cohorts, NR2C2AP Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NR2C2AP data layer compared with 24 for mass-spec protein and 6 for mass-spec protein.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher NR2C2AP Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated NR2C2AP expression acts as an unfavorable survival marker.
HNSC, KIRC, and UCEC are the cancer types where NR2C2AP Mutation most reproducibly stratifies survival.
Mutation survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.