Across TCGA patient cohorts, NR2C2AP mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NR2C2AP-associated genes across cancer lineages are PR, IGFBP2, and Ku80. Each is linked with NR2C2AP in more than 1 cancer types. Because this analysis shows association rather than direction, both NR2C2AP-to-partner and partner-to-NR2C2AP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NR2C2AP→partner) and Y-score (partner→NR2C2AP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PR →	-0.297	-3.000	.040	.037	2	1
UCEC	IGFBP2 →	-0.847	-3.000	.024	.037	1	1
UCEC	Ku80 →	+0.337	+3.013	.013	.019	1	1
UCEC	p62 Lck ligand →	+0.445	+3.000	.018	.037	1	1
UCEC	TFRC →	+0.643	+3.000	.036	.037	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

NR2C2AP survival (RNA) · tumor vs normal (RNA) · all NR2C2AP data types