NR2C1

Across TCGA cell cohorts, NR2C1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,378 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NR2C1-associated GO terms across cancer lineages are Positive regulation of retinoic acid receptor signaling pathway, Spliceosomal complex assembly, and Cold acclimation. Each is linked with NR2C1 in more than 11 cancer types. Because this analysis shows association rather than direction, both NR2C1-to-partner and partner-to-NR2C1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of retinoic acid receptor signaling pathway grouped by NR2C1-low versus NR2C1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NR2C1→partner) and Y-score (partner→NR2C1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Positive regulation of retinoic acid receptor signaling pathway →	+0.167	+0.713	<.001	<.001	3	12
LUNG_SCLC	Spliceosomal complex assembly →	+0.091	+0.734	<.001	<.001	3	11
PANCREAS	Cold acclimation →	+0.188	+0.902	<.001	<.001	3	11
BONE	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.115	+0.630	.003	.003	3	10
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.099	+0.732	.003	.002	3	10
BONE	Late viral transcription →	+0.089	+0.639	.008	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,378 associations by consensus.

Positive regulation of retinoic acid receptor signaling pathway by NR2C1 expression — KIDNEY

Explore this box plot interactively →