NR1I3

Across TCGA cell cohorts, NR1I3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,719 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NR1I3-associated GO terms across cancer lineages are Positive regulation of monoatomic ion transmembrane transport, Regulation of potassium ion transport, and Host-mediated activation of viral process. Each is linked with NR1I3 in more than 12 cancer types. Because this analysis shows association rather than direction, both NR1I3-to-partner and partner-to-NR1I3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of monoatomic ion transmembrane transport grouped by NR1I3-low versus NR1I3-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NR1I3→partner) and Y-score (partner→NR1I3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of monoatomic ion transmembrane transport →	-0.119	-0.802	<.001	.003	3	13
OVARY	Regulation of potassium ion transport →	-0.141	-0.455	<.001	.001	3	12
OVARY	Host-mediated activation of viral process →	+0.081	+0.432	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Negative regulation of gene expression, epigenetic →	+0.076	+1.078	<.001	.001	3	12
OESOPHAGUS	ATP biosynthetic process →	+0.125	+0.348	.003	<.001	3	12
OESOPHAGUS	Establishment of protein localization to organelle →	+0.057	+0.353	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,719 associations by consensus.

Positive regulation of monoatomic ion transmembrane transport by NR1I3 expression — LIVER

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