NR1I2

Across TCGA cell cohorts, NR1I2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,326 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NR1I2-associated GO terms across cancer lineages are Fatty acid catabolic process, Fatty acid oxidation, and Lipid oxidation. Each is linked with NR1I2 in more than 7 cancer types. Because this analysis shows association rather than direction, both NR1I2-to-partner and partner-to-NR1I2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Fatty acid catabolic process grouped by NR1I2-low versus NR1I2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NR1I2→partner) and Y-score (partner→NR1I2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Fatty acid catabolic process →	+0.078	+1.806	.009	<.001	2	8
LIVER	Fatty acid oxidation →	+0.091	+1.703	<.001	.002	2	8
LIVER	Lipid oxidation →	+0.079	+1.703	.003	.002	2	8
STOMACH	Regulation of tolerance induction dependent upon immune response →	+1.563	+3.246	<.001	<.001	3	6
LARGE_INTESTINE	SREBP signaling pathway →	+0.183	+2.378	<.001	<.001	3	6
LARGE_INTESTINE	Cellular response to sterol depletion →	+0.112	+1.669	.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,326 associations by consensus.

Fatty acid catabolic process by NR1I2 expression — LIVER

Explore this box plot interactively →