NR1H4

Across TCGA patient cohorts, NR1H4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,959 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible NR1H4-associated GO terms across cancer lineages are Regulation of very-low-density lipoprotein particle remodeling, Organophosphate catabolic process, and Nucleoside bisphosphate biosynthetic process. Each is linked with NR1H4 in more than 15 cancer types. Because this analysis shows association rather than direction, both NR1H4-to-partner and partner-to-NR1H4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of very-low-density lipoprotein particle remodeling grouped by NR1H4-low versus NR1H4-high in KICH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NR1H4→partner) and Y-score (partner→NR1H4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KICH	Regulation of very-low-density lipoprotein particle remodeling →	+0.934	+0.972	<.001	<.001	3	16
ESCA	Organophosphate catabolic process →	+0.043	+0.668	<.001	<.001	3	14
ESCA	Nucleoside bisphosphate biosynthetic process →	+0.050	+0.674	<.001	<.001	3	14
ESCA	Citrate metabolic process →	+0.053	+0.558	<.001	<.001	3	13
SARC	Regulation of protein complex stability →	+0.055	+0.484	<.001	.004	3	13
STAD	Peroxisome organization →	+0.047	+0.584	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,959 associations by consensus.

Regulation of very-low-density lipoprotein particle remodeling by NR1H4 expression — KICH

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