NR0B2

Across TCGA cell cohorts, NR0B2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. CNS shows the largest number of these associations.

The most reproducible NR0B2-associated genes across cancer lineages are SPINK9, KRTAP9-1, and SMIM28. Each is linked with NR0B2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NR0B2-to-partner and partner-to-NR0B2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPINK9 grouped by NR0B2-low versus NR0B2-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NR0B2→partner) and Y-score (partner→NR0B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	SPINK9 →	+0.057	+5.321	<.001	.005	3	1
CNS	KRTAP9-1 →	+0.090	+4.981	<.001	.008	3	1
CNS	SMIM28 →	+0.060	+5.321	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

SPINK9 by NR0B2 expression — CNS

Explore this box plot interactively →