NPY5R

Across TCGA patient cohorts, NPY5R mutation is significantly associated with the RNA expression of many other genes, with 2,338 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NPY5R-associated genes across cancer lineages are SLC25A3P3, RBM22P12, and OR6K5P. Each is linked with NPY5R in more than 3 cancer types. Because this analysis shows association rather than direction, both NPY5R-to-partner and partner-to-NPY5R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC25A3P3 grouped by NPY5R-low versus NPY5R-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPY5R→partner) and Y-score (partner→NPY5R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SLC25A3P3 →	+0.046	+1.579	<.001	<.001	3	4
LIHC	RBM22P12 →	+0.224	+5.878	<.001	.002	3	3
READ	OR6K5P →	+0.033	+4.672	.001	.004	3	3
SKCM	TTC39CP1 →	+0.035	+2.193	<.001	.003	3	3
SKCM	RNA5SP422 →	+0.027	+3.495	<.001	.008	3	3
SKCM	GTF2IP3 →	+0.155	+1.421	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,338 associations by consensus.

SLC25A3P3 by NPY5R expression — SKCM

Explore this box plot interactively →