NPY5R

Across TCGA cell cohorts, NPY5R RNA expression is significantly associated with the go_rna of many other GO terms, with 2,162 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NPY5R-associated GO terms across cancer lineages are Negative regulation of acute inflammatory response to antigenic stimulus, T-helper 17 type immune response, and T-helper 17 cell differentiation. Each is linked with NPY5R in more than 4 cancer types. Because this analysis shows association rather than direction, both NPY5R-to-partner and partner-to-NPY5R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of acute inflammatory response to antigenic stimulus grouped by NPY5R-low versus NPY5R-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPY5R→partner) and Y-score (partner→NPY5R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of acute inflammatory response to antigenic stimulus →	-0.357	-2.320	<.001	<.001	3	5
BONE	T-helper 17 type immune response →	+0.117	+1.446	<.001	.007	3	5
STOMACH	T-helper 17 cell differentiation →	+0.166	+0.033	<.001	.009	2	5
SOFT_TISSUE	Cell fate determination →	-0.116	-0.147	.005	.002	3	3
SKIN	Swimming behavior →	+0.119	+0.071	<.001	.007	3	3
SKIN	Monocarboxylic acid transport →	-0.067	-0.067	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,162 associations by consensus.

Negative regulation of acute inflammatory response to antigenic stimulus by NPY5R expression — BONE

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