NPY5R

Across TCGA cell cohorts, NPY5R mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible NPY5R-associated genes across cancer lineages are OCM2, OR7G2, and PRAMEF11. Each is linked with NPY5R in more than 1 cancer types. Because this analysis shows association rather than direction, both NPY5R-to-partner and partner-to-NPY5R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OCM2 grouped by NPY5R-low versus NPY5R-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPY5R→partner) and Y-score (partner→NPY5R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OCM2 →	+0.069	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR7G2 →	+0.012	+4.887	.004	.009	3	1
LUNG_NSCLC_LUAD	PRAMEF11 →	+0.006	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	GRIFIN →	+0.042	+4.887	<.001	.009	3	1
LARGE_INTESTINE	CD300H →	+0.033	+4.415	<.001	.007	3	1
SKIN	PAGE4 →	+0.616	+3.242	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

OCM2 by NPY5R expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →