Across TCGA pan-cancer cohorts, NPY4R Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated NPY4R data layer compared with 22 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher NPY4R Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated NPY4R expression acts as an unfavorable survival marker.

OV and SKCM are the cancer types where NPY4R Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	II,III,IV	0.076	0.844	<.001	48	view →
SKCM	OS	Median	II,III,IV	0.072	0.843	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: NPY4R tumor-vs-normal RNA expression · all NPY4R data types