Across TCGA cell cohorts, NPY4R mutation is significantly associated with the mutation status of many other genes, with 2,894 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NPY4R-associated genes across cancer lineages are TICRR, ZNF648, and HUWE1. Each is linked with NPY4R in more than 3 cancer types. Because this analysis shows association rather than direction, both NPY4R-to-partner and partner-to-NPY4R results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPY4R→partner) and Y-score (partner→NPY4R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TICRR →	+3.063	+3.498	.006	.006	1	4
SKIN	ZNF648 →	+5.357	+4.392	<.001	<.001	1	4
LUNG_NSCLC_LUAD	HUWE1 →	+3.117	+4.491	.004	.004	1	4
LARGE_INTESTINE	TULP4 →	+2.080	+3.906	.003	.003	1	4
LARGE_INTESTINE	CNGA3 →	+2.781	+4.504	<.001	<.001	1	4
LUNG_NSCLC_LUAD	CACNA1D →	+4.339	+4.339	.009	.009	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,894 associations by consensus.

Exploration

NPY4R survival (RNA) · tumor vs normal (RNA) · all NPY4R data types