NPY

Across TCGA patient cohorts, NPY protein abundance is significantly associated with the RNA expression of many other genes, with 5,400 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NPY-associated genes across cancer lineages are ECRG4, VIPR2, and TSPAN7. Each is linked with NPY in more than 2 cancer types. Because this analysis shows association rather than direction, both NPY-to-partner and partner-to-NPY results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NPY versus ECRG4 in OV, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPY→partner) and Y-score (partner→NPY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ECRG4 →	+2.062	+0.343	.003	.009	3	3
GBM	VIPR2 →	+1.461	+1.133	.003	.001	3	3
LUAD	TSPAN7 →	+0.763	+0.440	.004	.007	3	3
GBM	CDH19 →	+1.102	+0.867	<.001	<.001	3	3
CCRCC	RBP4 →	+1.860	+0.511	.001	.007	3	3
OV	AP3B2 →	+0.641	+0.374	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,400 associations by consensus.

NPY vs ECRG4 — OV

Explore this scatter interactively →