NPY

Across TCGA cell cohorts, NPY RNA expression is significantly associated with the go_rna of many other GO terms, with 2,348 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NPY-associated GO terms across cancer lineages are Adult feeding behavior, Synaptic signaling via neuropeptide, and Negative regulation of acute inflammatory response to antigenic stimulus. Each is linked with NPY in more than 7 cancer types. Because this analysis shows association rather than direction, both NPY-to-partner and partner-to-NPY results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adult feeding behavior grouped by NPY-low versus NPY-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPY→partner) and Y-score (partner→NPY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Adult feeding behavior →	+2.125	+4.160	<.001	<.001	3	8
BONE	Synaptic signaling via neuropeptide →	+1.318	+3.447	<.001	<.001	3	6
LUNG_SCLC	Negative regulation of acute inflammatory response to antigenic stimulus →	-0.288	-1.869	<.001	.004	3	6
BONE	DNA-templated transcription initiation →	+0.075	+3.117	<.001	<.001	3	6
LUNG_SCLC	mRNA transport →	+0.094	+1.996	.001	.001	3	6
BONE	Calcium ion transport →	-0.047	-2.637	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,348 associations by consensus.

Adult feeding behavior by NPY expression — BONE

Explore this box plot interactively →