Across TCGA patient cohorts, NPW mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible NPW-associated genes across cancer lineages are TSEN15P3, TTTY7, and CDY1B. Each is linked with NPW in more than 1 cancer types. Because this analysis shows association rather than direction, both NPW-to-partner and partner-to-NPW results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPW→partner) and Y-score (partner→NPW) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TSEN15P3 →	+0.079	+7.816	<.001	.008	3	1
SKCM	TTTY7 →	+0.019	+7.816	<.001	.008	3	1
SKCM	CDY1B →	+0.014	+7.816	<.001	.008	3	1
SKCM	RNU6-456P →	+0.248	+7.816	<.001	.008	3	1
SKCM	ARL2BPP7 →	+0.119	+7.816	<.001	.008	3	1
SKCM	RNU6-1261P →	+0.253	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

NPW survival (RNA) · tumor vs normal (RNA) · all NPW data types