Across TCGA patient cohorts, NPTXR mutation is significantly associated with the RNA expression of many other genes, with 3,762 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NPTXR-associated genes across cancer lineages are ACTR3P3, MRGPRX9P, and MIR551A. Each is linked with NPTXR in more than 2 cancer types. Because this analysis shows association rather than direction, both NPTXR-to-partner and partner-to-NPTXR results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPTXR→partner) and Y-score (partner→NPTXR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ACTR3P3 →	+0.046	+4.798	<.001	.006	3	3
SKCM	MRGPRX9P →	+0.040	+3.743	<.001	.002	3	3
LUAD	MIR551A →	+0.523	+4.194	.002	.009	3	3
BRCA	SPATA31A5 →	+0.003	+7.471	<.001	.008	3	2
SKCM	LINC01525 →	+0.029	+3.897	<.001	.009	3	2
SKCM	LINC00674 →	+0.730	+3.341	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,762 associations by consensus.

Exploration

NPTXR survival (RNA) · tumor vs normal (RNA) · all NPTXR data types