NPTX1

Across TCGA patient cohorts, NPTX1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,296 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NPTX1-associated genes across cancer lineages are VIPR2, DNAJC6, and PAIP2B. Each is linked with NPTX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NPTX1-to-partner and partner-to-NPTX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NPTX1 versus VIPR2 in GBM, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPTX1→partner) and Y-score (partner→NPTX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	VIPR2 →	+1.638	+0.920	<.001	<.001	3	2
GBM	DNAJC6 →	+1.157	+0.988	<.001	<.001	3	2
GBM	PAIP2B →	+1.342	+0.758	<.001	<.001	3	2
GBM	TULP4 →	+0.547	+0.761	<.001	<.001	3	2
LUAD	HABP4 →	+0.510	+1.372	.002	.001	3	2
GBM	FAIM2 →	+1.011	+0.828	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,296 associations by consensus.

NPTX1 vs VIPR2 — GBM

Explore this scatter interactively →