NPTX1

Across TCGA cell cohorts, NPTX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,435 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible NPTX1-associated GO terms across cancer lineages are Cell cycle G1/S phase transition, Poly(A)+ mRNA export from nucleus, and Postsynaptic density assembly. Each is linked with NPTX1 in more than 6 cancer types. Because this analysis shows association rather than direction, both NPTX1-to-partner and partner-to-NPTX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell cycle G1/S phase transition grouped by NPTX1-low versus NPTX1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPTX1→partner) and Y-score (partner→NPTX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cell cycle G1/S phase transition →	+0.079	+0.889	<.001	.004	3	7
OESOPHAGUS	Poly(A)+ mRNA export from nucleus →	+0.090	+1.124	<.001	.005	3	7
UPPER_AERODIGESTIVE_TRACT	Postsynaptic density assembly →	-0.223	-0.882	<.001	.003	3	6
UPPER_AERODIGESTIVE_TRACT	G1/S transition of mitotic cell cycle →	+0.080	+0.895	<.001	.004	3	5
LIVER	Membrane depolarization during action potential →	-0.090	-0.264	<.001	.004	3	5
OESOPHAGUS	Microtubule cytoskeleton organization involved in mitosis →	+0.127	+1.688	.002	.009	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,435 associations by consensus.

Cell cycle G1/S phase transition by NPTX1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →