NPS

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NPS RNA expression is significantly associated with the go_rna of many other GO terms, with 5,225 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NPS-associated GO terms across cancer lineages are Respiratory system development, Protein localization to ciliary membrane, and rRNA modification. Each is linked with NPS in more than 4 cancer types. Because this analysis shows association rather than direction, both NPS-to-partner and partner-to-NPS results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPS→partner) and Y-score (partner→NPS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADRespiratory system development →+0.136+0.049<.001.00235
STADProtein localization to ciliary membrane →+0.101+0.112<.001<.00135
STADrRNA modification →+0.188+0.056<.001<.00135
STADMaturation of SSU-rRNA →+0.229+0.107<.001<.00135
STADPositive regulation of cellular response to insulin stimulus →+0.177+0.102<.001<.00134
STADNegative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway →+0.125+0.051<.001.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,225 associations by consensus.

Exploration