NPRL3

Across TCGA patient cohorts, NPRL3 protein abundance is significantly associated with the RNA expression of many other genes, with 3,619 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible NPRL3-associated genes across cancer lineages are HUS1, MIR3125, and TXN2. Each is linked with NPRL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NPRL3-to-partner and partner-to-NPRL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NPRL3 versus HUS1 in OV, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPRL3→partner) and Y-score (partner→NPRL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HUS1 →	-0.442	-0.352	.009	.002	3	2
UCEC	MIR3125 →	+1.420	+0.203	<.001	.002	3	2
COAD	TXN2 →	+0.499	+0.560	.003	.001	3	2
COAD	ANKRD61 →	-0.762	-0.625	.002	.006	3	2
COAD	UQCR10 →	+0.836	+0.669	<.001	.002	3	2
COAD	THOC7-AS1 →	-0.442	-0.627	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,619 associations by consensus.

NPRL3 vs HUS1 — OV

Explore this scatter interactively →