NPRL3

Across TCGA cell cohorts, NPRL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,581 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NPRL3-associated GO terms across cancer lineages are Metanephric proximal tubule development, Symbiont-mediated disruption of host cell PML body, and DNA replication-dependent chromatin assembly. Each is linked with NPRL3 in more than 11 cancer types. Because this analysis shows association rather than direction, both NPRL3-to-partner and partner-to-NPRL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Metanephric proximal tubule development grouped by NPRL3-low versus NPRL3-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPRL3→partner) and Y-score (partner→NPRL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Metanephric proximal tubule development →	+0.208	+0.827	<.001	<.001	3	12
BONE	Symbiont-mediated disruption of host cell PML body →	+0.104	+1.115	<.001	<.001	3	12
LARGE_INTESTINE	DNA replication-dependent chromatin assembly →	+0.117	+0.919	<.001	<.001	3	12
BONE	Regulation of chromatin organization →	+0.114	+0.733	<.001	<.001	3	11
LARGE_INTESTINE	Telomerase RNA stabilization →	+0.104	+0.977	<.001	<.001	3	10
LUNG_NSCLC_LUSC	rRNA pseudouridine synthesis →	+0.146	+0.942	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,581 associations by consensus.

Metanephric proximal tubule development by NPRL3 expression — LARGE_INTESTINE

Explore this box plot interactively →