NPRL2

Across TCGA cell cohorts, NPRL2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,901 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NPRL2-associated GO terms across cancer lineages are Response to flavonoid, UTP metabolic process, and Positive regulation of DNA repair. Each is linked with NPRL2 in more than 9 cancer types. Because this analysis shows association rather than direction, both NPRL2-to-partner and partner-to-NPRL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to flavonoid grouped by NPRL2-low versus NPRL2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPRL2→partner) and Y-score (partner→NPRL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Response to flavonoid →	+0.236	+1.212	<.001	<.001	3	10
CNS	UTP metabolic process →	+0.112	+0.436	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Positive regulation of DNA repair →	+0.055	+0.712	.002	.002	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of cAMP-dependent protein kinase activity →	+0.834	+0.595	.004	.007	3	8
KIDNEY	Regulation of DNA strand elongation →	+0.078	+0.724	.001	<.001	3	7
LUNG_SCLC	Arginyl-tRNA aminoacylation →	+0.164	+0.630	<.001	<.001	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,901 associations by consensus.

Response to flavonoid by NPRL2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →