NPPC

Across TCGA cell cohorts, NPPC RNA expression is significantly associated with the RNA expression of many other genes, with 6,235 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NPPC-associated genes across cancer lineages are CERS1, GPSM1, and EFNB3. Each is linked with NPPC in more than 6 cancer types. Because this analysis shows association rather than direction, both NPPC-to-partner and partner-to-NPPC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NPPC versus CERS1 in LIVER, with a Pearson correlation of 0.73.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NPPC→partner) and Y-score (partner→NPPC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	CERS1 →	+2.708	+0.739	<.001	<.001	3	5
STOMACH	GPSM1 →	+1.909	+0.900	<.001	.007	1	7
OESOPHAGUS	EFNB3 →	+2.473	+1.147	<.001	.001	2	6
LUNG_NSCLC_LUSC	TSPAN33 →	+2.009	+0.476	.001	.004	2	6
LUNG_SCLC	CASP4 →	-2.898	-1.163	<.001	<.001	3	4
STOMACH	NSG1 →	+2.300	+0.937	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,235 associations by consensus.

NPPC vs CERS1 — LIVER

Explore this scatter interactively →