NPPC

Across TCGA cell cohorts, NPPC RNA expression is significantly associated with the go_rna of many other GO terms, with 2,462 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NPPC-associated GO terms across cancer lineages are Cellular response to glycoprotein, Growth plate cartilage chondrocyte proliferation, and Regulation of oocyte maturation. Each is linked with NPPC in more than 17 cancer types. Because this analysis shows association rather than direction, both NPPC-to-partner and partner-to-NPPC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to glycoprotein grouped by NPPC-low versus NPPC-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPPC→partner) and Y-score (partner→NPPC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Cellular response to glycoprotein →	+1.277	+2.647	<.001	<.001	3	18
OESOPHAGUS	Growth plate cartilage chondrocyte proliferation →	-0.395	-1.140	.009	<.001	3	17
LUNG_SCLC	Regulation of oocyte maturation →	-0.288	-1.290	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Transcription initiation at RNA polymerase II promoter →	+0.086	+0.284	<.001	<.001	3	10
STOMACH	mRNA transport →	+0.081	+0.658	<.001	.006	3	8
BREAST	Protein-DNA complex organization →	+0.051	+0.527	<.001	.002	1	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,462 associations by consensus.

Cellular response to glycoprotein by NPPC expression — SKIN

Explore this box plot interactively →