NPPB

Across TCGA patient cohorts, NPPB protein abundance is significantly associated with the protein abundance of many other proteins, with 873 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NPPB-associated proteins across cancer lineages are TBC1D1, TBC1D10B_S22, and TBC1D23_T562. Each is linked with NPPB in more than 1 cancer types. Because this analysis shows association rather than direction, both NPPB-to-partner and partner-to-NPPB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NPPB versus TBC1D1 in UCEC, with a Pearson correlation of 0.61.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NPPB→partner) and Y-score (partner→NPPB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TBC1D1 →	+0.595	+0.489	<.001	<.001	3	2
UCEC	TBC1D10B_S22 →	+0.428	+0.454	<.001	.001	3	1
UCEC	TBC1D23_T562 →	+0.653	+0.563	<.001	.002	3	1
UCEC	TMCO4 →	+0.425	+0.536	<.001	<.001	3	1
UCEC	TNS3_S901 →	+0.855	+0.804	<.001	.001	3	1
UCEC	TOM1_S160 →	+0.710	+0.548	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 873 associations by consensus.

NPPB vs TBC1D1 — UCEC

Explore this scatter interactively →