NPPB

Across TCGA cell cohorts, NPPB RNA expression is significantly associated with the go_rna of many other GO terms, with 1,335 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NPPB-associated GO terms across cancer lineages are Positive regulation of mitotic cell cycle phase transition, Positive regulation of blood pressure by epinephrine-norepinephrine, and Protein K11-linked ubiquitination. Each is linked with NPPB in more than 7 cancer types. Because this analysis shows association rather than direction, both NPPB-to-partner and partner-to-NPPB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitotic cell cycle phase transition grouped by NPPB-low versus NPPB-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPPB→partner) and Y-score (partner→NPPB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Positive regulation of mitotic cell cycle phase transition →	+0.076	+3.364	.003	.007	3	8
BLOOD_Lymphoma	Positive regulation of blood pressure by epinephrine-norepinephrine →	+0.540	+0.056	.004	.001	3	7
BLOOD_Lymphoma	Protein K11-linked ubiquitination →	+0.036	+0.037	.006	.004	3	7
KIDNEY	Establishment of protein localization to membrane →	+0.048	+3.170	<.001	.001	3	7
LUNG_NSCLC_LUSC	Regulation of renal sodium excretion →	+1.754	+4.828	.005	.004	3	7
BONE	Potassium ion transport →	-0.055	-2.504	<.001	.008	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,335 associations by consensus.

Positive regulation of mitotic cell cycle phase transition by NPPB expression — LIVER

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