NPM1P51

Across TCGA pan-cancer cohorts, NPM1P51 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated NPM1P51 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher NPM1P51 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NPM1P51 expression acts as an unfavorable survival marker, although some lineages such as UCS and KIRC show a favorable association.

KICH, MESO, and STAD are the cancer types where NPM1P51 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Tertile	III,IV	0.219	0.798	.002	102	view →
MESO	OS	Median	All	0.386	0.627	<.001	90	view →
STAD	DFS	Tertile	All	0.570	0.881	<.001	55	view →
KIRP	OS	Tertile	All	0.814	0.904	.014	21	view →
LUSC	DFS	Median	II,III,IV	0.503	0.788	.008	16	view →
UCS	DFS	Tertile	IV	0.981	0.540	.025	12	view →
KIRC	DFS	Median	All	0.935	0.807	.012	11	view →
SKCM	OS	Quartile	III,IV	0.910	0.623	.017	11	view →
OV	OS	Tertile	II,III,IV	0.860	0.780	.011	10	view →
UVM	DFS	Tertile	III,IV	0.157	0.715	.007	9	view →
SARC	OS	Tertile	All	0.658	0.777	.009	9	view →
READ	DFS	Tertile	III,IV	0.953	0.605	.027	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

NPM1P51–KICH (OS)

Open the KICH breakdown →