NPM1P40

Across TCGA pan-cancer cohorts, NPM1P40 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated NPM1P40 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher NPM1P40 RNA is associated with better overall survival. In most high-consensus cancer types, elevated NPM1P40 expression acts as an unfavorable survival marker, although some lineages such as THCA and READ show a favorable association.

THCA, KICH, and ESCA are the cancer types where NPM1P40 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Median	All	0.996	0.958	.003	25	view →
KICH	OS	Quartile	All	0.739	0.966	.004	23	view →
ESCA	DFS	Quartile	All	0.401	0.655	.004	23	view →
KIRC	DFS	Median	IV	0.232	0.470	.008	21	view →
LIHC	OS	Tertile	II,III,IV	0.517	0.774	.004	19	view →
CHOL	DFS	Tertile	All	0.116	0.671	.007	15	view →
LGG	DFS	Tertile	All	0.736	0.868	.006	12	view →
MESO	DFS	Median	IV	0.223	0.490	.020	12	view →
STAD	OS	Quartile	II,III,IV	0.542	0.786	.026	9	view →
READ	DFS	Tertile	III,IV	0.824	0.332	.018	9	view →
UVM	DFS	Quartile	III,IV	0.396	0.818	.016	8	view →
THYM	DFS	Quartile	II,III,IV	0.806	0.992	.013	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

NPM1P40–THCA (OS)

Open the THCA breakdown →