NPM1P37

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, NPM1P37 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of NPM1P37’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where NPM1P37 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NPM1P37 is over-expressed in tumor.

KIRC, LUAD, and COAD are the cancer types where NPM1P37 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NPM1P37 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRCFemaleII,III,IV+0.257<.00110view →
LUADAllAll+0.382<.0017view →
COADMaleII,III,IV+0.328<.0016view →
BRCAAllAll+0.141.0114view →
LIHCAllAll+0.078<.0013view →
BLCAAllIII,IV+0.343.0192view →
PRADAllAll+0.227<.0012view →
CHOLAllAll+0.325.0471view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

Exploration