Q-omics provides the consensus-scored NPM1P37 profile across patient tissues and cancer cell-line models. NPM1P37 expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in ESCA. Among the 18 cancer types available for tumor–normal comparison, NPM1P37 is differentially expressed in 8, with the highest sampling consensus in KIRC. Additionally, NPM1P37 RNA expression shows 17,170 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight ESCA, KIRC, and UVM as cancer lineages where NPM1P37 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for NPM1P37 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes NPM1P37 survival associations across molecular data types. NPM1P37 RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible NPM1P37 RNA expression–survival associations across cancer types. High NPM1P37 expression shows unfavorable associations in ESCA, KICH, MESO and LUSC, but favorable associations in SKCM and READ. The ESCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify ESCA as the clearest survival context for NPM1P37 RNA expression.
This table summarizes NPM1P37 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for NPM1P37. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. NPM1P37 shows higher tumor expression in KIRC, LUAD, COAD, BRCA, LIHC and BLCA. The KIRC box plot shows higher NPM1P37 RNA expression in tumor versus normal tissue (log2 FC = +0.257, t-test p < 0.001).
This table shows molecular features associated with NPM1P37 in patient tissues and cancer cell lines. In patient samples, NPM1P37 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
