NPM1P28

Across TCGA patient cohorts, NPM1P28 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,543 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NPM1P28-associated GO terms across cancer lineages are rRNA modification, Positive regulation of DNA metabolic process, and Regulation of microtubule cytoskeleton organization. Each is linked with NPM1P28 in more than 9 cancer types. Because this analysis shows association rather than direction, both NPM1P28-to-partner and partner-to-NPM1P28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, rRNA modification grouped by NPM1P28-low versus NPM1P28-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NPM1P28→partner) and Y-score (partner→NPM1P28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	rRNA modification →	+0.047	+0.054	<.001	<.001	3	10
STAD	Positive regulation of DNA metabolic process →	+0.052	+0.067	<.001	<.001	3	10
UCEC	Regulation of microtubule cytoskeleton organization →	+0.041	+0.041	<.001	<.001	3	10
STAD	Signal transduction in response to DNA damage →	+0.053	+0.056	<.001	<.001	3	10
STAD	Ribosomal large subunit assembly →	+0.053	+0.057	<.001	<.001	3	9
STAD	Regulation of double-strand break repair via homologous recombination →	+0.051	+0.065	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,543 associations by consensus.

rRNA modification by NPM1P28 expression — STAD

Explore this box plot interactively →