NPM1P28

Across TCGA pan-cancer cohorts, NPM1P28 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated NPM1P28 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher NPM1P28 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NPM1P28 expression acts as an unfavorable survival marker, although some lineages such as COAD and LUAD show a favorable association.

CESC, PAAD, and KIRC are the cancer types where NPM1P28 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Tertile	II,III,IV	0.217	0.775	<.001	108	view →
PAAD	DFS	Tertile	All	0.084	0.486	<.001	90	view →
KIRC	OS	Tertile	All	0.688	0.832	<.001	66	view →
KICH	OS	Tertile	All	0.155	0.926	<.001	63	view →
SKCM	DFS	Tertile	II,III,IV	0.238	0.614	<.001	54	view →
THYM	OS	Tertile	II,III,IV	0.169	0.905	<.001	54	view →
ACC	OS	Tertile	All	0.113	0.822	<.001	39	view →
LIHC	DFS	Tertile	III,IV	0.125	0.375	.003	36	view →
PCPG	OS	Tertile	All	0.078	0.849	<.001	27	view →
COAD	OS	Tertile	All	1.000	0.590	.013	21	view →
LUSC	OS	Tertile	IV	0.001	0.651	.025	18	view →
KIRP	DFS	Tertile	II,III,IV	0.122	0.626	.032	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

NPM1P28–CESC (OS)

Open the CESC breakdown →